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tryptophan$85550$ - translation to English
CLASS OF ENZYMES
Tryptophan 5-monooxygenase; Tryptophan-5-hydroxylase; EC 1.14.16.4; Tryptophan 5-hydroxylase; L-tryptophan,tetrahydrobiopterin:oxygen oxidoreductase (5-hydroxylating)
tryptophan
n. Tryptophan (Biochemie- eine Aminosäure)
Definition
tryptophan
['tr?pt?fan]
¦ noun Biochemistry an amino acid which is a constituent of most proteins and is an essential nutrient in the diet of vertebrates.
Origin
C19: from tryptic 'relating to trypsin' + Gk phainein 'appear'.
Wikipedia
Tryptophan hydroxylase
Tryptophan hydroxylase (TPH) is an enzyme (EC 1.14.16.4) involved in the synthesis of the neurotransmitter serotonin. Tyrosine hydroxylase, phenylalanine hydroxylase, and tryptophan hydroxylase together constitute the family of biopterin-dependent aromatic amino acid hydroxylases. TPH catalyzes the following chemical reaction
- L-tryptophan + tetrahydrobiopterin + O2 5-Hydroxytryptophan + dihydrobiopterin + H2O
It employs one additional cofactor, iron.
